Origins of Metastatic Traits
22. května 2014 | Mendel Lectures
Začátek v 17:00 v Mendelově muzeu.
Vstup zdarma. Jazyk přednášky angličtina.
Joan Massagué is interested in the mechanisms that support tissue homeostasis and cancer metastasis. Focusing on transforming growth factor-β (TGFβ) as one of the most prevalent signaling pathways in metazoan biology, he elucidated this signaling pathway and is establishing how TGFβ signals control pluripotency and differentiation in stem cell and homeostasis in mature cells. He is also interested in how cancer cells co-opt this and other pathways for metastases. His goal is to use this basic knowledge for treating cancer.